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Category : Anti Depressants
Name of brand : Anafranil Clonil Tridep Clomipraminum Hydiphen Monochlorimipramine : Anafranil Brands- Quality meds - without a prior Rx at med-store.co
Name of generic : Clomipramine HCI
Title : Generic Anafranil (Clomipramine HCI)
Short descriptions : Anafranil (Clomipramine HCI) is a tricyclic antidepressant used to treat depression and obsessive-compulsive disorder.
 
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Full description prescription Anafranil Clomipramine HCI

Brand name:
Anafranil (Clomipramine)
Pronounced: an-AF-ran-il
Generic name: Clomipramine hydrochloride
Why is Anafranil (Clomipramine) prescribed?

Anafranil (Clomipramine) , a chemical cousin of tricyclic antidepressant medications such as Tofranil and Elavil, is used to treat people who suffer from obsessions and compulsions.

An obsession is a persistent, disturbing idea, image, or urge that keeps coming to mind despite the person's efforts to ignore or forget it--for example, a preoccupation with avoiding contamination.

A compulsion is an irrational action that the person knows is senseless but feels driven to repeat again and again--for example, hand-washing perhaps dozens or even scores of times throughout the day.
Most important fact about Anafranil (Clomipramine) without prescriptions

Serious, even fatal, reactions have been known to occur when drugs such as Anafranil (Clomipramine) are taken along with drugs known as MAO inhibitors. Drugs in this category include the antidepressants Nardil and Parnate. Never take Anafranil (Clomipramine) with one of these drugs.
How should you take Anafranil (Clomipramine) ?

Take Anafranil (Clomipramine) with meals, at first, to avoid stomach upset. After your regular dosage has been established, you can take 1 dose at bedtime to avoid sleepiness during the day. Always take it exactly as prescribed.

This medicine may cause dry mouth. Hard candy, chewing gum, or bits of ice may relieve this problem.

If you miss a dose Anafranil (Clomipramine)

If you take 1 dose at bedtime, consult your doctor. Do not take the missed dose in the morning. If you take 2 or more doses a day, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at the same time.

Storage instructions Anafranil (Clomipramine)

Store at room temperature in a tightly closed container, away from moisture.
Anafranil (Clomipramine) side effects

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Anafranil (Clomipramine) .

The most significant risk is that of seizures (convulsions). Headache, fatigue, and nausea can be a problem. Men are likely to experience problems with sexual function. Unwanted weight gain is a potential problem for many people who take Anafranil (Clomipramine) , although a small number actually lose weight.

* Side effects may include:
Constipation, dizziness, dry mouth, impotence, increased appetite, increased sweating, indigestion, libido changes, nausea, nervousness, sleepiness, tremor, twitching, visual changes, weight gain, weight loss

Why should Anafranil (Clomipramine) not be prescribed?

Do not take Anafranil (Clomipramine) if you are sensitive to or have ever had an allergic reaction to a tricyclic antidepressant such as Tofranil, Elavil, or Tegretol.

Be sure to avoid Anafranil (Clomipramine) if you are taking, or have taken within the past 14 days, an MAO inhibitor such as the antidepressants Parnate or Nardil. Combining Anafranil (Clomipramine) with one of these medications could lead to fever, seizures, coma, and even death.

Do not take Anafranil (Clomipramine) if you have recently had a heart attack.
Special warnings about Anafranil (Clomipramine)

This drug should be used with caution in children with depression. In clinical studies, antidepressants increased the risk of suicidal thinking and behavior in children and adolescents with depression and other psychiatric disorders. Anyone considering the use of Anafranil (Clomipramine) or any other antidepressant in a child or adolescent must balance this risk with the clinical need. In children, Anafranil (Clomipramine) is only approved to treat obsessive-compulsive disorder.

Additionally, the progression of major depression is associated with a worsening of symptoms and/or the emergence of suicidal thinking or behavior in both adults and children, whether or not they are taking antidepressants. Individuals being treated with Anafranil (Clomipramine) and their caregivers should watch for any change in symptoms or any new symptoms that appear suddenly--especially agitation, anxiety, hostility, panic, restlessness, extreme hyperactivity, and suicidal thinking or behavior--and report them to the doctor immediately. Be especially observant at the beginning of treatment or whenever there is a change in dose.

If you have narrow-angle glaucoma (increased pressure in the eye) or are having difficulty urinating, Anafranil (Clomipramine) could make these conditions worse. Use Anafranil (Clomipramine) with caution if your kidney function is not normal.

If you have a tumor of the adrenal gland, Anafranil (Clomipramine) could cause your blood pressure to rise suddenly and dangerously.

Because Anafranil (Clomipramine) poses a possible risk of seizures, and because it may impair mental or physical ability to perform complicated tasks, your doctor will probably warn you to take special precautions if you need to drive a car, operate complicated machinery, or take part in activities such as swimming or climbing, in which suddenly losing consciousness could be dangerous. Note that your risk of seizures is increased:

* If you have ever had a seizure
* If you have a history of brain damage or alcoholism
* If you are taking another medication that might predispose you to seizures

As with Tofranil, Elavil, and other tricyclic antidepressants, an overdose of Anafranil (Clomipramine) can be fatal. Do not be surprised if your doctor prescribes only a small quantity of Anafranil (Clomipramine) at a time. This is standard procedure to minimize the risk of overdose.

Anafranil (Clomipramine) may cause your skin to become more sensitive to sunlight. Avoid prolonged exposure to sunlight.

Before having any kind of surgery involving the use of general anesthesia, tell your doctor or dentist that you are taking Anafranil (Clomipramine) . You may be advised to discontinue the drug temporarily.

When it is time to stop taking Anafranil (Clomipramine) , do not stop abruptly. Your doctor will have you taper off gradually to avoid withdrawal symptoms such as dizziness, fever, general feeling of illness, headache, high fever, irritability or worsening emotional or mental problems, nausea, sleep problems, vomiting.
Possible food and drug interactions when taking Anafranil (Clomipramine)

Avoid alcoholic beverages while taking Anafranil (Clomipramine) .

If Anafranil (Clomipramine) is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Anafranil (Clomipramine) with the following:
Antipsychotic drugs such as Haldol and chlorpromazine
Barbiturates such as phenobarbital
Certain blood pressure drugs such as Ismelin and Catapres-TTS
Cimetidine (Tagamet)
Digoxin (Lanoxin)
Drugs that ease spasms, such as Donnatal, Cogentin, and Bentyl
Flecainide (Tambocor)
Methylphenidate (Ritalin)
MAO inhibitors such as Nardil and Parnate
Phenytoin (Dilantin)
Propafenone (Rythmol)
Quinidine (Quinidex)
Serotonin-boosting drugs such as the antidepressants Luvox, Paxil, Prozac and Zoloft
Thyroid medications such as Synthroid
Tranquilizers such as Xanax and Valium
Warfarin (Coumadin)
Special information if you are pregnant or breastfeeding

If you are pregnant or plan to become pregnant, inform your doctor immediately. Anafranil (Clomipramine) should not be used during pregnancy unless absolutely necessary; some babies born to women who took Anafranil (Clomipramine) have had withdrawal symptoms such as jitteriness, tremors, and seizures. Anafranil (Clomipramine) appears in breast milk. Your doctor may advise you to stop breastfeeding while you are taking Anafranil (Clomipramine) .
Recommended dosage for Anafranil (Clomipramine)

ADULTS
Overdosage

An overdose of Anafranil (Clomipramine) can be fatal. If you suspect an overdose, seek medical attention immediately.

* Critical signs and symptoms of Anafranil (Clomipramine) overdose may include:
Impaired brain activity (including coma), irregular heartbeat, seizures, severely low blood pressure

* Other signs and symptoms of overdosage may include:
Agitation, bluish skin color, breathing difficulty, delirium, dilated pupils, drowsiness, high fever, incoordination, little or no urine output, muscle rigidity, overactive reflexes, rapid heartbeat, restlessness, severe perspiration, shock stupor, twitching or twisting movements, vomiting

There is a danger of heart malfunction and even, in rare cases, cardiac arrest.

What is the most important information I should know about Anafranil?

  • While you are taking Anafranil you may need to be monitored for worsening symptoms of depression and/ or suicidal thoughts at the start of therapy or when doses are changed. This concern about the increased risk of suicidal thoughts or behaviors may be greater if you are 18 years of age or younger and are taking Anafranil. In patients younger than 18 years, the period of risk may extend beyond start of therapy or when doses are changed. Your doctor may want you to monitor for the following symptoms: anxiety, panic attacks, difficulty sleeping, irritability, hostility, impulsivity, severe restlessness, and mania (mental and/ or physical hyperactivity). These symptoms may be associated with the development of worsening symptoms of depression and/ or suicidal thoughts or actions. Contact your healthcare provider if you develop any new or worsening mental health symptoms during treatment with Anafranil. Do not stop taking Anafranil.
  • It may be 4 weeks or more before you start to feel better, but do not stop taking Anafranil without first talking to your doctor.
  • Use caution when driving, operating machinery, or performing other hazardous activities. Anafranil may cause drowsiness or dizziness. If you experience drowsiness or dizziness, avoid these activities.
  • Dizziness is likely to occur when you rise from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall.
  • Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking Anafranil.

What is Anafranil?

  • Anafranil is in a class of drugs called tricyclic antidepressants. Anafranil affects chemicals in the brain that may become unbalanced and cause obsessive-compulsive disorder.
  • Anafranil is used to relieve symptoms of obsessive-compulsive disorder such as recurrent thoughts or feelings and repetitive actions.
  • Anafranil may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before taking Anafranil?

  • Do not take Anafranil if you have taken a monoamine oxidase inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) within the last 14 days.
  • Before taking Anafranil, tell your doctor if you have
    • liver disease,
    • kidney disease,
    • asthma,
    • thyroid disease,
    • diabetes,
    • stomach or intestinal problems,
    • high blood pressure or heart disease,
    • had a heart attack in the last 6 weeks,
    • an enlarged prostate or difficulty urinating,
    • glaucoma, or
    • seizures.
  • You may not be able to take Anafranil, or you may require a dosage adjustment or special monitoring during therapy if you have any of the conditions listed above.
  • While you are taking Anafranil you may need to be monitored for worsening symptoms of depression and/ or suicidal thoughts at the start of therapy or when doses are changed. This concern about the increased risk of suicidal thoughts or behaviors may be greater if you are 18 years of age or younger and are taking Anafranil. In patients younger than 18 years, the period of risk may extend beyond start of therapy or when doses are changed. Your doctor may want you to monitor for the following symptoms: anxiety, panic attacks, difficulty sleeping, irritability, hostility, impulsivity, severe restlessness, and mania (mental and/ or physical hyperactivity). These symptoms may be associated with the development of worsening symptoms of depression and/ or suicidal thoughts or actions. Contact your healthcare provider if you develop any new or worsening mental health symptoms during treatment with Anafranil. Do not stop taking Anafranil.
  • Anafranil is in the FDA pregnancy category C. This means that it is not known whether Anafranil will harm an unborn baby. Do not take Anafranil without first talking to your doctor if you are pregnant or could become pregnant during treatment.
  • Anafranil passes into breast milk and may affect a nursing baby. Do not take Anafranil without first talking to your doctor if you are breast-feeding a baby.

How should I take Anafranil?

  • Take Anafranil exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
  • Take each dose with a full glass (8 oz) of water.
  • Anafranil may be taken several times a day or in one daily dose (usually at bedtime). Follow your doctor's instructions.
  • Grapefruit and grapefruit juice may interact with Anafranil. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.
  • It may be 4 weeks or more before you start to feel better, but do not stop taking Anafranil without first talking to your doctor.
  • Store Anafranil at room temperature away from moisture and heat.

What happens if I miss a dose?

  • Take the missed dose as soon as you remember. If it is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not take a double dose of this medication unless otherwise directed by your doctor.

What happens if I overdose?

  • Seek emergency medical attention.
  • Symptoms of a Anafranil overdose include seizures, confusion, drowsiness, agitation, hallucinations, and low blood pressure (dizziness, fatigue, fainting).

What should I avoid while taking Anafranil?

  • Use caution when driving, operating machinery, or performing other hazardous activities. Anafranil may cause drowsiness or dizziness. If you experience drowsiness or dizziness, avoid these activities.
  • Dizziness is likely to occur when you rise from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall.
  • Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking Anafranil.
  • Grapefruit and grapefruit juice may interact with Anafranil. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.
  • Do not stop taking Anafranil suddenly. This could cause symptoms such as nausea, headache, and malaise.

What are the possible side effects of Anafranil?

  • If you experience any of the following serious side effects, stop taking Anafranil and contact your doctor immediately or seek emergency medical treatment:
    • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, face, or tongue; or hives);
    • seizures;
    • a fast or irregular heartbeat;
    • a heart attack;
    • high blood pressure (blurred vision, severe headache);
    • difficulty urinating; or
    • fever with increased sweating, muscle stiffness, or severe muscle weakness.
  • Other, less serious side effects may be more likely to occur. Continue to take Anafranil and talk to your doctor if you experience
    • drowsiness or dizziness;
    • dry mouth and eyes;
    • constipation;
    • mild tremor;
    • sweating;
    • mild agitation, weakness, or headache;
    • ringing in the ears;
    • nausea; or
    • loss of weight or appetite.
  • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Anafranil?

  • Do not take Anafranil if you have taken a monoamine oxidase inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) within the last 14 days.
  • Anafranil may increase the effects of other drugs that cause drowsiness, including other antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, and muscle relaxants. Tell your doctor about all medicines that you are taking, and do not take any other prescription or over-the-counter medicines without first talking to your doctor.
  • Drugs other than those listed here may also interact with Anafranil. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.

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