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Short descriptions : Fosamax (Alendronate) is a bisphosphonate used to prevent and treat osteoporosis. It may also be used to treat paget's disease, steroid-induced osteoporosis, and other conditions as determined by your doctor.
Fosamax is prescribed for the prevention and treatment of osteoporosis,
the brittle bone disease, in postmenopausal women. It is also used
to increase bone mass in men with osteoporosis, and is prescribed for
both men and women who have developed a form of osteoporosis sometimes
caused by steroid medications such as prednisone. This drug can also
be used to relieve Paget's disease of bone, a painful condition that
weakens and deforms the bones. Most important fact about Fosamax
For Fosamax to be effective, you must take the tablets without food
or other medications, exactly as directed. How should you use medication?
Fosamax is effective only when each tablet or bottle of oral solution
is taken with a full glass of plain water first thing in the morning,
at least 30 minutes before the first food, beverage, or other medication.
If you can wait longer before eating or drinking, Fosamax will be absorbed
better. Do not lie down after taking Fosamax until at least 30 minutes
have passed and you've had something to eat.
Avoid chewing or sucking on the tablet; it can cause mouth sores.
You should take calcium and vitamin D supplements if you don't get
enough in your diet. Avoid smoking and alcohol. Weight-bearing exercise
can also strengthen bones.
Storage instructions...
Keep the container tightly closed and store at room temperature. Do
not freeze the oral solution.
Fosamax side effects
Side effects cannot be anticipated. If any develop or change in intensity,
inform your doctor as soon as possible. Only your doctor can determine
if it is safe for you to continue using Fosamax.
* Side effects may include:
Abdominal pain, Acid regurgitation, bone and joint pain, constipation, diarrhea,
gas, indigestion, muscle pain, nausea
Why should Fosamax not be prescribed?
You should not take Fosamax if the calcium level in your blood is
low. Avoid Fosamax if it causes an allergic reaction.
You will not be able to take Fosamax if you are unable to stand or
sit upright for at least 30 minutes. You must also avoid the drug if
your esophagus is not working properly due to strictures or achalasia
(a swallowing disorder).
If you're prone to swallowing air or choking when you drink something,
you should not use the oral solution.
Special warnings about Fosamax
Fosamax is not recommended for women on hormone
replacement therapy, or for women with kidney problems.
Be sure to tell your doctor if you have trouble swallowing or have
any digestive problems, including heartburn or ulcers. Fosamax may
cause problems in your esophagus such as inflammation, ulcers, bleeding,
and in rare cases, blockage or perforation.
Possible food and drug interactions when taking Fosamax
Combining aspirin with a Fosamax dose of more than 10 milligrams per
day will increase the likelihood of stomach upset.
Calcium supplements such as Caltrate, antacids such as Riopan, and
some other oral medications will interfere with the absorption of Fosamax,
so wait at least 30 minutes after taking Fosamax before you take anything
else.
Special information if you are pregnant or breastfeeding
The effects of Fosamax during pregnancy and breastfeeding have not
been adequately studied. If you are pregnant or plan to become pregnant,
notify your doctor immediately. It is not known whether Fosamax appears
in breast milk. The drug is not recommended for nursing mothers.
Recommended dosage for Fosamax
TREATMENT OF POSTMENOPAUSAL OSTEOPOROSIS
Overdosage
Any medication taken in excess can have serious consequences. If you
suspect an overdose, seek medical attention immediately.
* Symptoms of Fosamax overdose may include:
Heartburn, inflammation of the esophagus or stomach, ulcer, upset stomach
If you miss a dose...
If you are taking Fosamax on a daily basis, do not take a missed
dose later in the day, Instead, skip it and go back to your regular
schedule the next morning.
If you are taking Fosamax once a week, take 1 tablet or 1 bottle
of oral solution the morning after you remember, then return to your
original once-weekly schedule on the chosen day. Do not take 2 doses
on the same day
What is the most important information I should know about Fosamax?
Do not take an Fosamax tablet if you cannot sit upright or stand for at least 30 minutes. Fosamax can cause serious problems in the stomach or esophagus (the tube that connects your mouth and stomach). You will need to stay upright for at least 30 minutes after taking this medication.
Take the Fosamax tablet first thing in the morning, at least 30 minutes before you eat or drink anything or take any other medicine.
Take each dose with a full glass (6 to 8 ounces) of water. Use only plain water (not mineral water) when taking an Fosamax tablet.
For at least the first 30 minutes after taking an Fosamax tablet, do not lie down or recline; do not eat or drink anything other than plain water; and do not take any other medicines including vitamins, calcium, or antacids.
Some people using medicines similar to Fosamax have developed bone loss in the jaw, also called osteonecrosis of the jaw. Symptoms of this condition may include jaw pain, swelling, numbness, loose teeth, gum infection, or slow healing after injury or surgery involving the gums. You may be more likely to develop osteonecrosis of the jaw if you have cancer or have been treated with chemotherapy, radiation, or steroids. Other conditions associated with osteonecrosis of the jaw include blood clotting disorders, anemia (low red blood cells), and a pre-existing dental problem.
Fosamax is only part of a complete program of treatment that may also include diet changes, exercise, and taking calcium and vitamin supplements. Follow your diet, medication, and exercise routines very closely.
What is Fosamax?
Fosamax is in the group of medicines called bisphosphonates (bis FOS fo nayts). It alters the cycle of bone formation and breakdown in the body. Fosamax slows bone loss while increasing bone mass, which may prevent bone fractures.
Fosamax is used to treat or prevent postmenopausal osteoporosis and steroid-induced osteoporosis. Fosamax is also used to treat Paget's disease of bone.
Fosamax may also be used for purposes other than those listed in this medication guide.
What should I discuss with my healthcare provider before taking Fosamax?
Do not take an Fosamax tablet if you cannot sit upright or stand for at least 30 minutes. Fosamax can cause serious problems in the stomach or esophagus (the tube that connects your mouth and stomach). You will need to stay upright for at least 30 minutes after taking this medication.
Before using Fosamax, tell your doctor if you have:
low blood calcium (hypocalcemia);
a vitamin D deficiency;
kidney disease; or
an ulcer in your stomach or esophagus.
If you have any of these conditions, you may not be able to use Fosamax, or you may need a dosage adjustment or special tests during treatment.
Some people using medicines similar to Fosamax have developed bone loss in the jaw, also called osteonecrosis of the jaw. Symptoms of this condition may include jaw pain, swelling, numbness, loose teeth, gum infection, or slow healing after injury or surgery involving the gums.
You may be more likely to develop osteonecrosis of the jaw if you have cancer or have been treated with chemotherapy, radiation, or steroids. Other conditions associated with osteonecrosis of the jaw include blood clotting disorders, anemia (low red blood cells), and dental surgery or pre-existing dental problems.
FDA pregnancy category C. This medication may be harmful to an unborn baby and should not be used by a woman who is pregnant. Tell your doctor if you become pregnant during treatment.
It is not known whether Fosamax passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
How should I take Fosamax?
Take Fosamax exactly as it was prescribed for you. Do not use the medication in larger amounts or for longer than recommended by your doctor.
Fosamax tablets are taken either once each day or once each week.
Take the Fosamax tablet first thing in the morning, at least 30 minutes before you eat or drink anything or take any other medicine. If you take an Fosamax tablet only once a week, take it on the same day each week and always first thing in the morning.
Take each Fosamax tablet with a full glass (6 to 8 ounces) of water. Use only plain water (not mineral water) when taking an Fosamax tablet.
Do not crush, chew, or suck the Fosamax tablet. Swallow the pill whole.
After taking an Fosamax tablet, carefully follow these instructions:
Do not lie down or recline for at least 30 minutes after taking Fosamax.
Do not eat or drink anything other than plain water.
Do not take any other medicines including vitamins, calcium, or antacids for at least 30 minutes after taking Fosamax. It may be best to take your other medicines at a different time of the day. Talk with your doctor about the best dosing schedule for your other medicines.
To be sure this medication is helping your condition, your bone mineral density will need to be tested on a regular basis. It is important that you not miss any scheduled visits to your doctor.
Fosamax is only part of a complete program of treatment that may also include diet changes, exercise, and taking calcium and vitamin supplements. Follow your diet, medication, and exercise routines very closely.
Store Fosamax tablets at room temperature away from moisture and heat.
What happens if I miss a dose?
If you take Fosamax tablets once daily: If you forget to take this medicine first thing in the morning, do not take it later in the day. Wait until the following morning to take the medicine and skip the missed dose. Do not take take two (2) tablets in one day.
If you take Fosamax tablets once a week: If you forget to take Fosamax on your scheduled day, take it first thing in the morning on the day after you remember the missed dose. Then return to your regular weekly schedule on your chosen dose day. Do not take take two (2) tablets in one day.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine. Drink a full glass of milk and call your local poison control left or emergency room right away. Do not make yourself vomit and do not lie down.
Symptoms of an Fosamax overdose may include nausea, heartburn, stomach pain, diarrhea, muscle cramps, numbness or tingling, tight muscles in your face, seizure (convulsions), irritability, and unusual thoughts or behavior.
What should I avoid while taking Fosamax?
Do not take any other medicines including vitamins, calcium, or antacids for at least 30 minutes after taking an Fosamax tablet.
Do not lie down for at least 30 minutes after you take an Fosamax tablet.
What are the possible side effects of Fosamax?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using Fosamax and call your doctor at once if you have any of these serious side effects:
chest pain;
difficulty or pain when swallowing;
pain or burning under the ribs or in the back;
new or worsening heartburn;
severe joint, bone, or muscle pain; or
jaw pain, numbness, or swelling.
Continue using Fosamax and talk with your doctor if you have any of these less serious side effects:
mild heartburn or stomach upset;
diarrhea, gas, or constipation;
mild joint or back pain; or
headache.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
What other drugs will affect Fosamax?
Antacids, supplements, or medicines that contain aluminum, calcium, magnesium, or other minerals can interfere with how your body absorbs Fosamax. If you use these other medicines, do not that take them for at least 30 minutes after taking an Fosamax tablet.
Before using Fosamax, tell your doctor if you also use aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as celecoxib (Celebrex), diclofenac (Voltaren), diflunisal (Dolobid), ibuprofen (Motrin, Advil), indomethacin, ketoprofen (Orudis), ketorolac (Toradol), naproxen (Aleve, Naprosyn), piroxicam (Feldene), and others.
There may be other drugs that can affect Fosamax. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
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